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Sleep & circadian rhythm
CORE SLEEP & RELAXATION PENDING CLINICAL VALIDATION

Sleep & circadian rhythm

Four ingredients that shorten the gap between lying down and falling asleep, and hold your night steady once you are there. It is a base formula, not a sedative: it works on the rhythm, not on knocking you out.

WHENNight, 30–60 min before sleep
WITH FOODNo. Away from your meal
DOSE VOLUME2.0 ml, in ten 0.2 ml pulses
INGREDIENTS4 active, 0 fillers
CARTRIDGE45 ml · up to 22 nights
SLOT1 of the 6 in your device

WHAT IS IN IT

Four actives. Nothing else.

These are the reference doses of the formula. Your device pours them in steps of 0.2 ml, so what you actually take on a given night can sit below the reference when your data does not call for the full dose.

INGREDIENTFORMPER DOSE% NRVWHAT IT IS THERE FOR
Melatonin—1 mg—Shortens the time it takes you to fall asleep
MagnesiumBisglycinate200 mg53%Normal function of the nervous system and normal psychological function
L-theanine—200 mg—Calm without sedation. Included on published evidence, not on an authorised claim
PassionflowerPassiflora incarnata500 mg—Traditional use for sleep onset. Its EU claim is still on hold
Total volume2.0 mlTen pulses of 0.2 ml, the smallest step the device can serve
Melatonin—1 mg—

Shortens the time it takes you to fall asleep

MagnesiumBisglycinate200 mg53% NRV

Normal function of the nervous system and normal psychological function

L-theanine—200 mg—

Calm without sedation. Included on published evidence, not on an authorised claim

PassionflowerPassiflora incarnata500 mg—

Traditional use for sleep onset. Its EU claim is still on hold

Total volume 2.0 ml 

Ten pulses of 0.2 ml, the smallest step the device can serve

No proprietary blends, no "complex" hiding the amounts, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.

No proprietary blends, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.

THE SCIENCE BEHIND IT

Two of these four have an
authorised claim. Two do not.
Two of these four have an authorised claim. Two do not.

In the EU, only a short list of health claims is authorised, and the rest of the register sits on hold. We would rather show you which of our ingredients are on that list and which are not than write a sentence that sounds the same for all four.In the EU, only a short list of health claims is authorised, and the rest of the register sits on hold. We would rather show you which of our ingredients are on that list and which are not.

Melatonin

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Melatonin contributes to the reduction of time taken to fall asleep.”

Regulation (EU) 432/2012. The claim only holds at 1 mg taken close to bedtime, which is exactly the dose in this formula. We did not round it up to look stronger.

Reg. 432/2012 · EFSA Journal 2011;9(6):2241 · 6 sources on file

Magnesium

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Magnesium contributes to normal functioning of the nervous system and to normal psychological function.”

Regulation (EU) 432/2012, which requires at least 15% of the NRV per dose. This formula carries 53%. The bisglycinate form is used for tolerance, not for a stronger claim.

Reg. 432/2012 · NRV 375 mg · 9 sources on file

L-theanine

NO AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

Nothing. We are not allowed to attribute an effect to it, so we do not.

It is here because the published work on 200 mg is consistent about calm without sedation, and because it pairs well with the magnesium. That is a reason to include it, not a permission to promise anything.

4 sources on file · 2 with a PMID · not a claim

Passionflower

ON HOLD IN THE EU REGISTER

WHAT WE ARE ALLOWED TO SAY

Nothing yet. Botanical claims are suspended pending review.

Traditional use for sleep onset, recognised by the EMA monograph but not by an authorised EFSA claim. If the register ever resolves it, we will update this page and say what changed.

EMA/HMPC monograph · 3 sources on file · claim on hold

HOW IT IS POURED

Ten pulses. Not always ten.

The full dose of this formula is 2.0 ml, which the device serves as ten pulses of 0.2 ml. On a night when your band says you do not need the whole thing, it pours seven and tells you why. A pressed pill has one setting. This has ten.

TONIGHT'S POUR

12345678910
1.4 ml of 2.0 mlyour HRV came back into band

NIGHT, 30–60 MIN BEFORE SLEEP

Why then

The melatonin claim only holds when it is taken close to bedtime. Earlier than that and the dose stops matching the evidence it rests on.

AWAY FROM YOUR MEAL

Why not with dinner

Magnesium and a full stomach compete. Other VION formulas ride on the fat of your dinner on purpose. This one does not.

45 ML CARTRIDGE

How long it lasts

At the full 2.0 ml it is 22 nights. At a partial pour it lasts longer, so the app orders your refill from what you actually took.

HOW IT ENTERS YOUR PLAN

A CORE formula is not suggested. It is assigned.

CORE is the part of your plan that stays still on purpose. It comes out of your questionnaire, not out of last night's sleep, and it is held long enough for a change to actually mean something.

  1. 01

    It comes from your questionnaire

    Your answers on sleep, schedule, stimulants and current medication put this formula in your base. No wearable data is needed for that first decision.

  2. 02

    It is held for at least 21 days

    Long enough for your own band to form and for a change to be a signal rather than noise. Nothing about this formula moves inside that window.

  3. 03

    Only the amount moves, night by night

    Once it is in, the engine adjusts how much of the 2.0 ml you get, in 0.2 ml steps, from your sleep and HRV of the last few days. The recipe itself does not change.

  4. 04

    It leaves when your questionnaire says so

    If your answers change at your next review, this cartridge comes out and its slot goes to whatever your base needs instead. You are told before it happens.

SAFETY AND INTERACTIONS

What it never shares a night with.

Every pair of ingredients in our library is checked against the others before a plan is built. This is what that check rules out for this formula.

NEVER TOGETHER

Relax & fast sleep

The BOOST version carries melatonin and magnesium too. The engine serves one or the other on a given night, never both, so your melatonin never doubles.

SPLIT ACROSS WINDOWS

Bones & joints

That formula also carries 200 mg of magnesium at night. Taken together they would pass the 250 mg upper limit for supplemental magnesium, so the two are moved apart.

TALK TO A DOCTOR FIRST

Not for everyone

Pregnancy and breastfeeding, liver disease, autoimmune conditions, under 18, and anyone on sedatives, anticoagulants or blood pressure medication. The app asks before it ever assigns this one.

WHERE THIS COMES FROM

Regulation (EU) 432/2012 on permitted health claims · EFSA Journal 2011;9(6):2241 on melatonin and sleep onset · EMA/HMPC monograph on Passiflora incarnata · EFSA tolerable upper intake level for supplemental magnesium. Every line on this page is tied to one of the 810 sources on file, and 443 of the 9,730 possible ingredient pairs in our library are documented so far.

WHERE IT COMES FROM

You can check every line of this page.

Four sources hold up this formula: the regulation that lets us make the claims, the EFSA opinion behind the melatonin dose, the EMA monograph for the botanical, and the upper limit we stay under.

REGULATIONRegulation (EU) 432/2012 — list of permitted health claims made on foodsclaims for melatonin and magnesium
EFSAEFSA Journal 2011;9(6):2241 — opinion on melatonin and reduction of sleep onset latencysets the 1 mg condition
EMAEMA/HMPC monograph — Passiflora incarnata L., herbatraditional use, claim on hold
EFSA ULTolerable upper intake level for supplemental magnesium — 250 mg per daywe serve 200 mg

WHAT IS NOT PROVEN YET

This formula has not completed clinical validation. Its four ingredients rest on published work and, in two cases, on an authorised EU claim, but the combination itself has not been tested by us in a trial. When it is, the result goes on this page, whatever it says.

YOU DO NOT PICK YOUR FORMULAS

Your data does.

The questionnaire and your first weeks of data decide which six of the 29 end up in your device. This page exists so you can read what one of them is before that happens.

Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition. Nothing here replaces a healthcare professional.

Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition.