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Muscle damage (CK)
ADAPT BLOODWORKIN DEVELOPMENT

Muscle damage (CK)

Six ingredients for the two weeks after a bout of muscle damage, when hard training or a minor injury pushes your creatine kinase (CK) up: curcumin with piperine, omega-3, magnesium, vitamin C and zinc, taken with dinner. It is still in development, and CK is not yet in our blood panel. None of the six has an authorised EU claim for muscle recovery: we would rather tell you that than let the name promise it.

WHENNight, with your dinner
WITH FOODYes, preferably. With your dinner
DOSE VOLUME2.8 ml, in fourteen 0.2 ml pulses
INGREDIENTS6 active, 0 fillers
CARTRIDGE45 ml · up to 16 nights
SLOT1 of the 6 in your device
See if it is in your plan Back to the library

WHAT IS IN IT

Six actives. Nothing else.

These are the reference doses of the formula, at the full 2.8 ml. Your device pours in steps of 0.2 ml, but the plan on file for this one is the full dose every night for two weeks. The composition record fixes only one chemical form, the magnesium bisglycinate; for the other five our ingredient files name a preferred form, but this formula does not set one, so the column is left empty. None of the six carries a claim for muscle recovery, and below we show what each one does carry.

INGREDIENTFORMPER DOSE% NRVWHAT IT IS THERE FOR
Curcumin—500 mg—No authorised claim. The EMA recognises turmeric for mild digestive complaints only, not for muscle recovery
Piperine—5 mg—No authorised claim. It is here to raise how much of the curcumin you absorb
EPA + DHA—2,000 mg—Normal function of the heart, from 250 mg a day. No claim covers muscle recovery
MagnesiumBisglycinate200 mg53%Normal muscle function, the only claim in this formula that mentions muscle
Vitamin C—200 mg250%Normal function of the immune system during and after intense exercise, at 200 mg a day
Zinc—10 mg100%Normal function of the immune system
Total volume2.8 mlFourteen pulses of 0.2 ml, the smallest step the device can serve
Curcumin—500 mg—

No authorised claim. The EMA recognises turmeric for mild digestive complaints only, not for muscle recovery

Piperine—5 mg—

No authorised claim. It is here to raise how much of the curcumin you absorb

EPA + DHA—2,000 mg—

Normal function of the heart, from 250 mg a day. No claim covers muscle recovery

MagnesiumBisglycinate200 mg53% NRV

Normal muscle function, the only claim in this formula that mentions muscle

Vitamin C—200 mg250% NRV

Normal function of the immune system during and after intense exercise, at 200 mg a day

Zinc—10 mg100% NRV

Normal function of the immune system

Total volume 2.8 ml 

Fourteen pulses of 0.2 ml, the smallest step the device can serve

No proprietary blends, no "complex" hiding the amounts, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.

No proprietary blends, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.

THE SCIENCE BEHIND IT

Four of these six have an authorised claim. None of them is about recovery.

In the EU, only a short list of health claims is authorised, and the rest of the register sits on hold. The name of this formula says what it is built for, not what it is allowed to promise. Magnesium is on the list for normal muscle function, the omega-3s for the heart, and vitamin C and zinc for the immune system. Curcumin and piperine are not on it at all. We would rather show you exactly what the list says than write a sentence that sounds the same for all six.

Curcumin

ON HOLD IN THE EU REGISTER

WHAT WE ARE ALLOWED TO SAY

Nothing yet. Botanical claims have been on hold in the EU since 2010, pending review.

The EMA monograph recognises turmeric for traditional use in mild digestive complaints, and advises seeing a doctor if symptoms last more than two weeks. It does not cover muscle recovery, so the use in this formula sits outside it. Our file names two trials, Drobnic 2014 and McFarlin 2016, that suggest less muscle soreness, with no regulatory claim behind them. Liver injury has been reported with high-absorption curcumin products, phytosomes and micelles among them, and piperine raises absorption too. The French agency ANSES advises staying under 153 mg of curcumin a day; our own curcumin file sets VION's maximum at 200 mg a day for absorption-enhanced curcumin; and the EFSA provisional ADI of 0–3 mg per kg of body weight works out at about 210 mg a day for a 70 kg adult. This formula carries 500 mg, above all three. We would rather show you that gap than hide it, and it is part of what clinical validation has to settle.

EMA/HMPC/329755/2017 · 7 sources on file · 1 with a PMID · claim on hold

Piperine

ON HOLD IN THE EU REGISTER

WHAT WE ARE ALLOWED TO SAY

Nothing yet. Black pepper is a botanical, and botanical claims have been on hold in the EU since 2010. It is not here for an effect of its own in any case.

Piperine, from black pepper, slows the breakdown of curcumin in your liver, which our library puts at around twenty times more curcumin reaching your blood. Our file keeps the two together on purpose. There is no EFSA upper limit for it, and the 5 mg here sits well under the 20 mg a day our own file allows. Our file also says it is not meant for continuous use beyond 12 weeks without supervision, which a 14-day course stays well inside. The same effect reaches many medicines too, which is why piperine sits behind several of the warnings further down this page.

Planta Medica 1998 (Shoba et al.) · 5 sources on file · 1 with a PMID · claim on hold

EPA + DHA

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“EPA and DHA contribute to the normal function of the heart.”

Regulation (EU) 432/2012, for a daily intake of 250 mg. This formula carries 2,000 mg, under the 5,000 mg upper limit. Our omega-3 file prefers a triglyceride or phospholipid form over an ethyl ester, but the composition record for this formula does not fix one. It is the claim this formula is filed under, and it is about your heart, not about your muscles. We would rather say that plainly. It comes from fish, and at this dose it is one of the reasons the formula is ruled out if you take an anticoagulant.

Reg. 432/2012 · 250 mg a day minimum · UL 5,000 mg · 2 sources on file · 2 with a PMID

Magnesium

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Magnesium contributes to normal muscle function.”

Regulation (EU) 432/2012, on a product that is at least a source of magnesium, which means 15% of the NRV per dose. 200 mg is 53%, as bisglycinate, the form our file prefers at night. It is the one claim in this formula that mentions muscle, and it is about normal function, not about repair. 200 mg also leaves only 50 mg of room under the 250 mg upper limit for supplemental magnesium, which is why this formula cannot share a day with any other VION formula that carries it.

Reg. 432/2012 · EFSA Journal 2009;7(9):1216 and 2010;8(10):1807 · NRV 375 mg · UL 250 mg · 14 sources on file

Vitamin C

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Vitamin C contributes to the normal function of the immune system during and after intense physical exercise.”

Regulation (EU) 432/2012, and only for a product that provides 200 mg of vitamin C a day, with the benefit coming from 200 mg a day on top of your recommended intake. The full dose here is exactly 200 mg, 250% of the NRV, and the plan on file is the full dose every night of the course. Our file counts it as relevant to repair after exercise, but the claim is about your immune system, not your muscles. EFSA has not set an upper limit for vitamin C; the US limit on file is 2,000 mg a day, and the German BfR suggests 250 mg in a supplement.

Reg. 432/2012 · EFSA Journal 2009;7(9):1226 · NRV 80 mg · 11 sources on file

Zinc

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Zinc contributes to the normal function of the immune system.”

Regulation (EU) 432/2012, which requires at least 15% of the NRV per dose. This formula carries 100%. At 10 mg you are at 40% of the EFSA upper limit of 25 mg a day, so the engine keeps a running total of your zinc across formulas. The German BfR suggests no more than 6.5 mg in a supplement, and this formula is above that. Like the vitamin C, it is here for the immune side of recovery, and its claim says nothing about muscle.

Reg. 432/2012 · EFSA Journal 2009;7(9):1229 · NRV 10 mg · UL 25 mg · 14 sources on file

HOW IT IS POURED

Fourteen pulses. Every night of the course.

The full dose of this formula is 2.8 ml, which the device serves as fourteen pulses of 0.2 ml. For some formulas, your band decides how many. For this one, no wearable marker in our library moves the dose: the plan on file is two weeks at the full dose, then a check. That also keeps the vitamin C at the 200 mg its exercise claim needs, which any partial pour would drop below.

TONIGHT'S POUR

1234567891011121314
2.8 ml of 2.8 mlthe full dose, every night of the course

NIGHT, WITH YOUR DINNER

Why then

Our file sets it for the night, with overnight muscle recovery as the reason, and our magnesium file puts the bisglycinate form at night anyway. Our curcumin file asks for a fatty meal for absorption, and our piperine file asks for food as well; the omega-3s are oil-soluble, though no food effect for them is on file. Food also makes the vitamin C easier on your stomach. Zinc would absorb a little better away from food and dairy, but the rest decides it: food wins.

AWAY FROM IRON

Why not with iron

Curcumin binds iron and cuts how much of it you absorb, so our library keeps the two at least two hours apart. Our zinc file adds that zinc and iron compete too, at 25 mg and above, though that pair is not one of the documented pairs in our matrix yet. The Iron formula goes out in the morning, before breakfast, and this one at night, so they never meet.

45 ML CARTRIDGE

How long it lasts

At the full 2.8 ml it is 16 nights, which covers one full 14-day course. The app works out what is left from what you actually took.

HOW IT ENTERS YOUR PLAN

An ADAPT formula starts with a blood test. This one is waiting for its marker.

ADAPT is the part of your plan that follows your bloodwork. It goes in when a result is out of range, runs for a fixed period at a fixed dose, and comes out when a new check says so. This one is written for creatine kinase (CK), a marker of muscle damage that is not yet part of the VION blood panel, which is one reason it is still in development.

  1. 01

    It follows an episode of muscle damage

    Our file writes it for the aftermath of hard training that pushes your CK above 500 U/L, or of a minor injury. It answers an episode. It is not something you stay on. Until CK is in our panel, no marker in our library is set to bring it in.

  2. 02

    Your profile is checked first

    Before it is ever assigned, your answers are checked against its exclusions. If you take an anticoagulant or have liver disease, it is ruled out, whatever your result says.

  3. 03

    It runs for two weeks

    14 days at the full dose. Two weeks is the limit the EMA monograph sets for turmeric, the ingredient that caps the course. Nothing about this formula moves inside that window.

  4. 04

    At two weeks, it stops and is reviewed

    Your CK and how sore you feel are checked again. If you have responded, it stops. If your CK stays high with no clear cause, the rule on file is a referral to a rheumatologist or a sports medicine doctor. A course can be repeated after a new episode. No official source sets a break between courses. Our own file allows no more than four courses a year, eight weeks of curcumin in total, for the sake of your liver, and that is VION's decision, not a regulator's rule.

SAFETY AND INTERACTIONS

What it never shares a night with.

Every pair of ingredients in our library is checked against the others before a plan is built. Inside this formula, two of its fifteen pairs are documented: curcumin with piperine, and vitamin C with zinc, both as pairings to keep together. The other thirteen are not documented yet. This is what the check rules out.

BLEEDING RISK FLAGGED

Cognitive & focus

That formula carries 120 mg of ginkgo. Ginkgo and curcumin both slow your platelets down, and our library only pairs them below 120 mg of ginkgo and 100 mg of curcumin, which these doses are not. Any plan with two such ingredients is flagged for bleeding risk, and blocked if you are on anticoagulants. The resveratrol in Systemic inflammation and Oxidative cardiovascular, and the vitamin E in Liver (ALT / AST), count too.

UPPER LIMIT TRACKED

Every other formula with magnesium or zinc

Nine other VION formulas carry magnesium, from 100 mg to 200 mg. With the 200 mg here, even the smallest takes you to 300 mg, past the 250 mg upper limit for supplemental magnesium, so the engine blocks the one that would take you over. Your zinc is added up the same way against its 25 mg limit: next to a formula with 15 mg, such as Acute immunity or Low testosterone, you would reach it, and the addition is stopped there. Systemic inflammation and Anti-inflammatory & recovery carry the same 500 mg of curcumin and 2,000 mg of omega-3, so any two of the three reach 1,000 mg of curcumin. Our dose table stores 1,000 mg a day as the EU limit for curcumin, but our own curcumin file puts VION's maximum at 200 mg a day for absorption-enhanced curcumin, in line with the French agency, and the EFSA provisional ADI works out at about 210 mg a day for a 70 kg adult. The 500 mg in this formula alone is already above both, and the two records in our library do not agree with each other. Curcumin and omega-3 are not yet on the list the engine adds up automatically, and that is one of the points clinical review has to close.

TALK TO A DOCTOR FIRST

Not for everyone

Not for you if you take an anticoagulant, including warfarin, acenocoumarol, apixaban or dabigatran; if you take several medicines at once, or if you are having chemotherapy, both of which our file blocks the piperine for; if you have liver disease; if you have a stomach ulcer or reflux; if you have a blocked bile duct or gallstones that cause symptoms; if you are pregnant or breastfeeding; if you are under 18; or if you are allergic to fish. Ask a doctor first if you take antiplatelets such as aspirin or clopidogrel, diabetes or blood pressure medication, statins (alone or with niacin), ciclosporin, tacrolimus or other immunosuppressants, digoxin or talinolol, phenytoin, carbamazepine, theophylline, propranolol, rifampicin, lithium, SSRIs or SNRIs, tamoxifen, amlodipine, antiretrovirals, the contraceptive pill or other oestrogens, bisphosphonates, tetracycline or quinolone antibiotics, penicillamine, diuretics, ACE inhibitors, aminoglycosides, amphotericin B, calcium channel blockers, levothyroxine, aluminium or other antacids, proton pump inhibitors long term, or deferoxamine; if you are due a general anaesthetic with muscle relaxants such as suxamethonium, which magnesium can add to. Piperine changes how your body handles many medicines, so bring the full list, and it is not meant for continuous use beyond 12 weeks without supervision. Bisphosphonates and tetracyclines need at least 2 hours apart, quinolones 2 hours before or 4–6 hours after, penicillamine at least 1 hour apart, and levothyroxine 4 hours. Ask first too if you have a bleeding disorder, kidney disease or kidney stones (magnesium is ruled out in advanced kidney disease), heart block or a slow heart rate, myasthenia gravis, haemochromatosis, thalassaemia or another iron overload, iron-deficiency anaemia, G6PD deficiency, histamine intolerance, Menkes disease, or a loss of smell or past use of zinc nasal products. Stop it at least two weeks before planned surgery. Stop it and see a doctor if you notice yellowing skin or eyes, unusual tiredness, abdominal pain or dark urine, and see one too if your symptoms last more than two weeks. It contains fish and is not suitable for vegans or vegetarians. Do not exceed the dose, do not use it in place of a varied and balanced diet, and keep it out of reach of young children. The app asks before it ever assigns this one.

WHERE THIS COMES FROM

Regulation (EU) 432/2012 on permitted health claims · Regulation (EU) 1169/2011 on nutrient reference values · EFSA opinions on vitamin C (2009), magnesium (2009 and 2010) and zinc (2009) · EMA/HMPC/329755/2017 monograph on Curcuma longa L., rhizoma · ANSES opinion on curcumin (2022) · EFSA tolerable upper intake levels for supplemental magnesium and for zinc. Every line on this page is tied to one of the 810 sources on file, and 443 of the 9,730 possible ingredient pairs in our library are documented so far.

WHERE IT COMES FROM

You can check every line of this page.

Eight sources hold up this formula: the regulation that lets us make four of the claims, the reference values behind the NRV column, the EFSA opinions behind three of those claims, the EMA monograph that caps the course at two weeks, the French alert on curcumin, the study behind the piperine, the upper limits we count against, and the German reference for zinc that this formula sits above.

REGULATIONRegulation (EU) 432/2012 — list of permitted health claims made on foodsclaims for EPA + DHA, magnesium, vitamin C and zinc
NRVRegulation (EU) 1169/2011, Annex XIII Part A — nutrient reference valuesmagnesium 375 mg, vitamin C 80 mg, zinc 10 mg
EFSA CLAIMSEFSA Journal 2009;7(9):1226 (vitamin C) · 2009;7(9):1216 and 2010;8(10):1807 (magnesium) · 2009;7(9):1229 (zinc)behind the exercise, muscle and immune claims
EMAEMA/HMPC/329755/2017 — European Union herbal monograph on Curcuma longa L., rhizoma (Revision 1), 2018digestive use only; see a doctor if symptoms last over two weeks
ANSESANSES (France), 2022 — opinion on the safety of curcumin in food supplementsliver alert, under 153 mg of curcumin a day
STUDYShoba G. et al., Planta Medica 1998 — Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteerswhy the piperine is there
UPPER LIMITSSupplemental magnesium 250 mg · zinc 25 mg · EPA + DHA 5,000 mg a day · curcumin 1,000 mg a day (the value stored in our dose table; our curcumin file sets VION's maximum at 200 mg a day for absorption-enhanced curcumin, and the EFSA provisional ADI works out at about 210 mg for a 70 kg adult)we serve 200 mg, 10 mg, 2,000 mg and 500 mg — the curcumin above the 200 mg and 210 mg figures
BfRBfR-Wissenschaft 03/2018 — Höchstmengenvorschläge für Vitamine und Mineralstoffe in Nahrungsergänzungsmittelnzinc 6.5 mg: this formula is above it

Reviewed by VION nutrition team · last reviewed 16 September 2026

WHAT IS NOT PROVEN YET

This formula is still in development and has not been through clinical validation. Four of its six ingredients carry authorised EU claims, but none of those claims is about muscle recovery or about bringing a CK result back into range, the EMA does not recognise turmeric for it, and the combination has not been tested by us in a trial. The two curcumin trials in our file suggest less soreness; they do not make a claim. Several points are still open: CK is not yet in our blood panel; the 500 mg of curcumin sits above the French reference of 153 mg, above the 200 mg a day our own curcumin file sets as VION's maximum for absorption-enhanced curcumin, and above the roughly 210 mg a day the EFSA provisional ADI gives for a 70 kg adult, while our dose table still stores 1,000 mg as the limit; and the engine does not yet add up curcumin and omega-3 across formulas. When they are settled, and when the formula is tested, the result goes on this page, whatever it says.

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YOU DO NOT PICK YOUR FORMULAS

Your data does.

The questionnaire and your first weeks of data decide which six of the 29 end up in your device. This page exists so you can read what one of them is before that happens.

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Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition. Nothing here replaces a healthcare professional.

Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition.