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Daily athletic
BOOST ENERGYPENDING CLINICAL VALIDATION

Daily athletic

Six ingredients for the mornings of a training season. Vitamin D3, magnesium and vitamin B6 carry EU claims on muscle function and protein metabolism. Ashwagandha, collagen and HMB carry none, and this page tells you why they are here anyway. It runs in 8-week cycles with a break, never more than three a year.

WHENMorning
WITH FOODPreferably. With breakfast
DOSE VOLUME1.0 ml, in five 0.2 ml pulses
INGREDIENTS6 active, 0 fillers
CARTRIDGE45 ml · up to 45 mornings
SLOT1 of the 6 in your device

WHAT IS IN IT

Six actives. Nothing else.

These are the reference doses of the formula. Your device pours them in steps of 0.2 ml, so what you actually take on a given morning can sit below the reference when your plan calls for less. In our interaction library, magnesium is recorded as complementary to ashwagandha, vitamin D3 and vitamin B6, and vitamin D3 with magnesium is a pairing it asks for outright.

INGREDIENTFORMPER DOSE% NRVWHAT IT IS THERE FOR
AshwagandhaRoot extract, KSM-66 (5% withanolides) or Sensoril600 mg—Included on 8-week trials at 300–600 mg, not on an authorised claim. This is the top of that range
Hydrolysed collagenType I + III (Verisol or equivalent)10 g—No authorised claim of its own. The EU claim on collagen formation belongs to vitamin C
HMBCalcium HMB monohydrate3 g—A metabolite of leucine. EFSA rejected all its claims
Vitamin D3Cholecalciferol10 µg200%Maintenance of normal muscle function
MagnesiumBisglycinate100 mg27%Normal muscle function and normal protein synthesis
Vitamin B6Pyridoxal-5-phosphate (P5P)1.4 mg100%Normal protein and glycogen metabolism
Total volume1.0 mlFive pulses of 0.2 ml, the smallest step the device can serve
AshwagandhaRoot extract, KSM-66 (5% withanolides) or Sensoril600 mg—

Included on 8-week trials at 300–600 mg, not on an authorised claim. This is the top of that range

Hydrolysed collagenType I + III (Verisol or equivalent)10 g—

No authorised claim of its own. The EU claim on collagen formation belongs to vitamin C

HMBCalcium HMB monohydrate3 g—

A metabolite of leucine. EFSA rejected all its claims

Vitamin D3Cholecalciferol10 µg200% NRV

Maintenance of normal muscle function

MagnesiumBisglycinate100 mg27% NRV

Normal muscle function and normal protein synthesis

Vitamin B6Pyridoxal-5-phosphate (P5P)1.4 mg100% NRV

Normal protein and glycogen metabolism

Total volume 1.0 ml 

Five pulses of 0.2 ml, the smallest step the device can serve

No proprietary blends, no "complex" hiding the amounts, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.

No proprietary blends, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.

THE SCIENCE BEHIND IT

Three of these six have an authorised claim. Three do not.

In the EU, only a short list of health claims is authorised. The three micronutrients in this formula are on it. HMB is not: EFSA looked at its claims and turned every one down. Collagen has none of its own, and ashwagandha, a botanical, has none either. We would rather show you which is which than write one sentence that sounds the same for all six.

Ashwagandha

NO AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

Nothing. Ashwagandha has no authorised EU claim, so we attribute no effect to it.

It is here because the standard trials on file, on stress and sleep, used 300–600 mg a day of standardised root extract for 8 weeks, and that is where the length of this cycle comes from. This formula carries 600 mg, the top of that range and the informal safety ceiling in our library, so any other ashwagandha formula on top would pass that ceiling. The engine's own rule blocks an addition at 1,200 mg a day, or after 90 days of continuous use. That is a reason to include it, not a permission to promise anything. Rare cases of liver injury are documented, and France's food safety agency, ANSES, advises against it in pregnancy, breastfeeding, under 18, thyroid disorders, hyperandrogenism, liver disease, heart disease and with sedatives. Every one of those rules this formula out.

No EU claim · ANSES 2024 · NIH ODS 2023 · 8 sources on file · 2 with a PMID

Hydrolysed collagen

NO AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

Nothing. EFSA turned down the claims made for collagen, and the EU claim on collagen formation belongs to vitamin C, not to collagen.

It is here at 10 g, inside the 2.5–15 g a day used in trials, where 10–15 g is the range studied for recovery. Our library records vitamin C as the cofactor your body needs to build collagen, and asks for at least 80 mg of it a day in any plan that carries collagen. This formula carries none, so that pairing depends on the rest of your plan, and we would rather tell you than leave it out. EFSA has set no upper limit for collagen.

No EU claim · no EFSA upper limit · 5 sources on file · 1 with a PMID

HMB

NO AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

Nothing. EFSA rejected every HMB claim it assessed, so we do not attribute an effect to it.

HMB is a metabolite of leucine, an amino acid. EFSA looked at claims on tissue damage, lean mass, strength, endurance, repair and recovery from fatigue, and turned all of them down. It is here at 3 g, the dose in our library, taken in the morning ahead of activity. Its file is still thin: no EFSA upper limit, no documented pair with any other ingredient, and not enough data on pregnancy and breastfeeding. That is a reason to include it with care, not a permission to promise anything.

EFSA Journal 2011;9(6):2227 · 2 sources on file · claim rejected

Vitamin D3

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Vitamin D contributes to the maintenance of normal muscle function.”

Regulation (EU) 432/2012, on condition that a dose is at least a source of vitamin D under Regulation (EC) 1924/2006. This formula carries 10 µg, 200% of the NRV, as cholecalciferol. Its upper limit is 100 µg a day, and it is in eight other VION formulas, at 25 to 62.5 µg, so your vitamin D is counted across your whole plan.

Reg. 432/2012 · EFSA Journal 2010;8(2):1468 · NRV 5 µg · 12 sources on file

Magnesium

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Magnesium contributes to normal muscle function.”

Regulation (EU) 432/2012, under the same condition. This formula carries 100 mg, 27% of the NRV, as bisglycinate, the form our notes prefer because it is gentle on the gut. Magnesium also carries the claim on normal protein synthesis. The upper limit for magnesium from supplements is 250 mg a day, and nine other VION formulas carry 100 to 200 mg of it.

Reg. 432/2012 · EFSA Journal 2009;7(9):1216 · NRV 375 mg · 14 sources on file

Vitamin B6

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Vitamin B6 contributes to normal protein and glycogen metabolism.”

Regulation (EU) 432/2012, under the same condition. This formula carries 1.4 mg, exactly 100% of the NRV, as P5P, the active form. B6 also carries the claim on the reduction of tiredness and fatigue. Its upper limit is 12 mg a day, one of the lowest among the vitamins, and it is in five other VION formulas, so your B6 is counted across your whole plan.

Reg. 432/2012 · EFSA Journal 2009;7(9):1225 · NRV 1.4 mg · 8 sources on file

HOW IT IS POURED

Five pulses. Not always five.

The full dose of this formula is 1.0 ml, which the device serves as five pulses of 0.2 ml. With only five, each pulse is a fifth of the dose, so the steps are coarse. When your plan calls for less, it pours fewer and tells you why, and it never serves a fraction of a pulse. No wearable signal decides the amount for this formula yet. When one does, this page will say which. A scoop has one setting. This has five.

TONIGHT'S POUR

12345
0.8 ml of 1.0 mlyour plan called for less this morning

MORNING

Why then

Our file puts this formula in the morning for three reasons: ashwagandha is used here as a daytime adaptogen, HMB is meant to come before activity, and collagen goes with breakfast. One note on file points the other way, and we would rather show it: for ashwagandha as a single high dose, our ingredient notes lean towards the evening. A clinician still has to settle that.

WITH BREAKFAST, PREFERABLY

Why with food

Vitamin D is fat-soluble and is absorbed better with a meal that contains some fat. Ashwagandha is gentler on your stomach with food, and B6 is better tolerated with it. Collagen works with or without a meal, and breakfast is simply where our file puts it.

45 ML CARTRIDGE

How long it lasts

At the full 1.0 ml it is 45 mornings, so an 8-week cycle takes a second cartridge. At a partial pour it lasts longer, so the app orders your refill from what you actually took.

HOW IT ENTERS YOUR PLAN

A BOOST formula is a cycle, not a base.

BOOST is the part of your plan that comes and goes, on top of your base. This one is put forward by what you tell us about your training, and it runs in 8-week cycles because that is the length of the trials behind its main ingredient.

  1. 01

    It comes from your answers on training

    Choosing daily sport as a goal, or telling us you train to compete, is what puts this formula forward. No wearable signal is linked to it yet. It is shown to you as a suggestion, and only after your answers on health and medication have been checked against its exclusions.

  2. 02

    It runs for 8 weeks

    That is 56 days, the standard length of the ashwagandha trials we hold. Inside that window only the amount can move, in 0.2 ml steps. The recipe itself does not change.

  3. 03

    At 8 weeks, it is reviewed

    Your training and how you feel are looked at again, and so are blood markers where they matter: your thyroid (TSH) if there is a thyroid risk, your liver enzymes (ALT and AST) if there is any doubt about your liver.

  4. 04

    Then 4 weeks off, and no more than 3 cycles a year

    No official source sets a break for ashwagandha, so the 4 weeks are our own clinical call, not a rule we can cite. The cap of 3 cycles a year, 24 weeks in all, is ours too, set out of caution for your liver. Separately, the engine stops ashwagandha from any formula after 90 days of continuous use.

SAFETY AND INTERACTIONS

What it is counted and checked against.

Every pair of ingredients in our library is checked against the others before a plan is built. Inside this formula, three of its fifteen possible pairs are documented, all as complementary: magnesium with vitamin D3, with vitamin B6 and with ashwagandha. HMB has no documented pair with anything yet. This is what the check does outside it.

COUNTED ACROSS FORMULAS

Stress & nervous system · Chronic cortisol · Low testosterone

All three carry ashwagandha too: 300 mg, 600 mg and 600 mg. The 600 mg here already sits at the informal safety ceiling in our library, so any of them on top would pass it. The engine adds up your ashwagandha across every formula and tracks how long you have taken it without a break. Stress & nervous system and Chronic cortisol also carry rhodiola. Our interaction library marks rhodiola with ashwagandha as a timing precaution: rhodiola in the morning, ashwagandha in the evening, and not in the same capsule.

COUNTED TOGETHER

Magnesium, vitamin D3, vitamin B6 and collagen

Nine other VION formulas carry magnesium. Eight of them would reach or pass the 250 mg upper limit for supplemental magnesium on the same day as this one, so the engine will not add them. Vitamin D3 is counted the same way against 100 µg a day, and held to 50 µg when it comes from three formulas, unless a clinician approves. B6 is counted against 12 mg. Skin, hair & nails carries another 10 g of collagen, and our notes put about 15 g a day as a sensible top, because of the protein load rather than a formal limit.

TALK TO A DOCTOR FIRST

Not for everyone

It is excluded if you are pregnant or breastfeeding, under 18, have liver disease or raised liver enzymes, heart disease, arrhythmias or high-grade heart block, a thyroid disorder (an overactive thyroid, Graves' disease, or a thyroid treated with levothyroxine) or hyperandrogenism, or if you take sedatives, benzodiazepines included, or a vitamin K antagonist such as warfarin or acenocoumarol. Avoid alcohol with it: our notes record ashwagandha and alcohol adding up as sedatives. Do not take it with immunosuppressants such as tacrolimus or ciclosporin, after a transplant, with St John's wort, or with drugs that load the liver (paracetamol, methotrexate, isoniazid). Do not stack it with another strong adaptogen such as ginseng or tulsi, with supplements that load the liver (kava, green tea extract) or act on the thyroid (seaweed with iodine, L-tyrosine), or with high-dose vitamin A. Stop it at any sign of liver trouble: yellowing skin, unusual tiredness, abdominal pain. Stop it 2 weeks before planned surgery. Ask a doctor first if you have an autoimmune condition (lupus, rheumatoid arthritis, multiple sclerosis, Hashimoto's), kidney disease (with advanced kidney disease, not at all), myasthenia gravis, peripheral neuropathy, sarcoidosis, lymphoma, primary hyperparathyroidism, granulomatous tuberculosis, high blood calcium or calcium kidney stones, histamine intolerance, or cancer or cancer treatment. The same applies if you take other anticoagulants such as apixaban or antiplatelets, psychiatric medication other than sedatives, diabetes or blood pressure medication, calcium-channel blockers, diuretics, digoxin, corticosteroids, statins, orlistat, anticonvulsants, levodopa without carbidopa, cycloserine, hydralazine, penicillamine, theophylline, the contraceptive pill, aminoglycosides or amphotericin B. On timing: keep magnesium 4 hours away from levothyroxine, keep bisphosphonates and tetracycline antibiotics at least 2 hours apart, take a quinolone antibiotic 2 hours before or 4 to 6 hours after it, keep iron of 25 mg or more apart from the magnesium, and do not swallow collagen in the same mouthful as levothyroxine, which in theory slows its absorption. Have your magnesium checked if you have taken a proton pump inhibitor for more than three months. The collagen comes from animal sources and may come from fish or egg: avoid it if you are allergic to its source. It is not suitable for vegans or vegetarians, nor halal or kosher unless certified. Do not exceed the daily dose, do not use it in place of a varied, balanced diet, and keep it out of reach of young children. The app asks before it ever suggests this one.

WHERE THIS COMES FROM

Regulation (EU) 432/2012 on permitted health claims · EFSA Journal 2011;9(6):2227 on HMB · ANSES 2024 opinion on ashwagandha · NIH ODS ashwagandha fact sheet (2023) · EFSA tolerable upper intake levels for supplemental magnesium, vitamin D and vitamin B6. Every line on this page is tied to one of the 810 sources on file, and 443 of the 9,730 possible ingredient pairs in our library are documented so far.

WHERE IT COMES FROM

You can check every line of this page.

Seven sources hold up this formula: the regulation behind its three claims, the EFSA opinion that turned down HMB, the French opinion behind its exclusions, the fact sheet behind its 8-week cycle, and the three upper limits the engine counts against.

REGULATIONRegulation (EU) 432/2012 — list of permitted health claims made on foodsclaims for vitamin D, magnesium and vitamin B6
EFSAEFSA Journal 2011;9(6):2227 — scientific opinion on β-hydroxy β-methylbutyrate (HMB)all claims rejected
ANSESANSES (France) 2024 — opinion on the risks of food supplements containing ashwagandha (Withania somnifera)the exclusions on this page
NIH ODSNIH Office of Dietary Supplements 2023 — Ashwagandha, Health Professional Fact Sheet8-week trials at 300–600 mg, basis of the cycle
EFSA ULEFSA 2006 — tolerable upper intake levels for vitamins and minerals: supplemental magnesium, 250 mg per daywe serve 100 mg
EFSA ULEFSA Journal 2023 — tolerable upper intake level for vitamin D, 100 µg per daywe serve 10 µg
EFSA ULEFSA Journal 2023 — tolerable upper intake level for vitamin B6, 12 mg per daywe serve 1.4 mg

Reviewed by VION nutrition team · last reviewed 16 September 2026

WHAT IS NOT PROVEN YET

This formula has not completed clinical validation. Three of its six ingredients rest on an authorised EU claim, and the other three on published work, one of them, HMB, with every claim turned down by EFSA. The combination itself has not been tested by us in a trial. When it is, the result goes on this page, whatever it says.

YOU DO NOT PICK YOUR FORMULAS

Your data does.

The questionnaire and your first weeks of data decide which six of the 29 end up in your device. This page exists so you can read what one of them is before that happens.

Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition. Nothing here replaces a healthcare professional.

Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition.