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Six B vitamins, each at 100% of its reference intake or more, and coenzyme Q10. Five of the six carry the EU claim on tiredness and fatigue. It is a morning base formula, not a stimulant: there is no caffeine in it.
WHAT IS IN IT
These are the reference doses of the formula. Your device pours them in steps of 0.2 ml, so what you actually take on a given morning can sit below the reference when your data does not call for the full dose.
Normal energy-yielding metabolism and normal function of the nervous system
Reduction of tiredness and fatigue, and normal energy-yielding metabolism
Reduction of tiredness and fatigue. The claim this formula is built around
Normal energy-yielding metabolism and reduction of tiredness and fatigue
Normal energy-yielding metabolism and normal psychological function
Reduction of tiredness and fatigue, and normal energy-yielding metabolism
No authorised claim. EFSA rejected every one submitted for it
Two pulses of 0.2 ml, the smallest step the device can serve
No proprietary blends, no "complex" hiding the amounts, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.
No proprietary blends, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.
THE SCIENCE BEHIND IT
In the EU, only a short list of health claims is authorised. The B vitamins are on it. Coenzyme Q10 is not, because EFSA rejected every claim submitted for it. We would rather show you that difference than write a sentence that sounds the same for all seven.
WHAT WE ARE ALLOWED TO SAY
“Thiamine contributes to normal energy-yielding metabolism.”
Regulation (EU) 432/2012, for a product that is at least a source of thiamine. This formula carries 100% of the NRV. Thiamine has no claim on tiredness and fatigue, so we do not borrow one for it. There is no EFSA upper limit, and the rare reactions on file are to injections, not to oral doses.
Reg. 432/2012 · EFSA Journal 2009;7(9):1222 · 2 sources on file
WHAT WE ARE ALLOWED TO SAY
“Riboflavin contributes to the reduction of tiredness and fatigue.”
Regulation (EU) 432/2012, for a product that is at least a source of riboflavin. This formula carries 100% of the NRV, as riboflavin-5-phosphate. It can turn your urine bright yellow. That is harmless: it is the riboflavin your body did not need, leaving.
Reg. 432/2012 · EFSA Journal 2010;8(10):1814 · 2 sources on file
WHAT WE ARE ALLOWED TO SAY
“Niacin contributes to the reduction of tiredness and fatigue.”
Regulation (EU) 432/2012. It is the claim this formula is built around, and it needs a product that is at least a source of niacin. This one carries 100% of the NRV. The form is nicotinamide, which does not cause the flushing that nicotinic acid can cause from 30 mg.
Reg. 432/2012 · EFSA Journal 2010;8(10):1757 · NRV 16 mg
WHAT WE ARE ALLOWED TO SAY
“Pantothenic acid contributes to normal energy-yielding metabolism.”
Regulation (EU) 432/2012, at 100% of the NRV. It also carries the claim on tiredness and fatigue. There is no EFSA upper limit for it.
Reg. 432/2012 · EFSA Journal 2009;7(9):1218 · NRV 6 mg
WHAT WE ARE ALLOWED TO SAY
“Vitamin B6 contributes to normal energy-yielding metabolism.”
Regulation (EU) 432/2012, at 100% of the NRV, as pyridoxal-5-phosphate. B6 has one of the lowest upper limits among the vitamins: EFSA set it at 12 mg a day in 2023. It is in five other VION formulas, so the engine adds up every milligram across your plan before it adds anything.
Reg. 432/2012 · EFSA Journal 2010;8(10):1759 · 8 sources on file
WHAT WE ARE ALLOWED TO SAY
“Vitamin B12 contributes to the reduction of tiredness and fatigue.”
Regulation (EU) 432/2012. The dose is 10 µg, 400% of the NRV, as methylcobalamin, the active form that needs no conversion. There is no EFSA upper limit for it.
Reg. 432/2012 · NRV 2.5 µg · 8 sources on file
WHAT WE ARE ALLOWED TO SAY
Nothing. EFSA rejected every claim submitted for it, so we do not attribute an effect to it.
CoQ10 is a compound your body makes itself. It carries electrons in the part of your cells that produces energy, and your own production falls with age and with statins. That is a reason to include it, not a permission to promise anything. The rejected claims covered energy, blood pressure, cognition, cholesterol and endurance, among others. There is no EFSA upper limit for CoQ10. The limit we apply in the EU comes from Germany's BfR: 100 mg a day, which is exactly what this formula carries. Our own notes, in line with France's ANSES, cap the total across formulas at 200 mg a day, and Cardiovascular and Oxidative cardiovascular carry 200 mg each. The engine does not add CoQ10 up across your plan yet, and how the plan handles that overlap is not documented yet.
EFSA Journal 2010;8(10):1793 · 9 sources on file · claim rejected
HOW IT IS POURED
The full dose of this formula is 0.4 ml, which the device serves as two pulses of 0.2 ml. On a morning when your band says you do not need the whole thing, it pours one and tells you why. Even at one pulse, every B vitamin stays at half its reference intake or more. A pressed pill has one setting. This has two.
TONIGHT'S POUR
MORNING
Some people report trouble sleeping when CoQ10 is taken late in the day, and our notes on B6 and B12 also favour the morning. So this one goes out with your first window, not your last.
WITH BREAKFAST
CoQ10 dissolves in fat, not in water, and it is absorbed better when your meal has some fat in it. B6 is also easier on the stomach with food.
45 ML CARTRIDGE
At the full 0.4 ml it is 112 mornings. At a partial pour it lasts longer, so the app orders your refill from what you actually took.
HOW IT ENTERS YOUR PLAN
CORE is the part of your plan that stays still on purpose. It comes out of your questionnaire, not out of yesterday's data, and it is held long enough for a change to actually mean something.
Choosing energy as one of your goals is what puts this formula in your base, after your answers on health and current medication have been checked. No wearable data is needed for that first decision.
Long enough for your own band to form and for a change to be a signal rather than noise. Nothing about this formula moves inside that window.
Once it is in, the engine decides whether you get one pulse or both, from your activity minutes and resting heart rate. The recipe itself does not change.
If you are still tired after three months of taking it, this formula is not the answer. The next step is a blood test for ferritin, B12 and TSH, to look for a cause it does not address, such as low iron.
SAFETY AND INTERACTIONS
Every pair of ingredients in our library is checked against the others before a plan is built. This is what that check does for this formula.
COUNTED ACROSS FORMULAS
B6 is also in five other VION formulas, and niacin is in Pre-workout. Before any formula is added, the engine adds up each of them across your plan and blocks the addition if it would pass the upper limit. For B6 that limit is 12 mg a day. For niacin, the EFSA limits are 10 mg a day as nicotinic acid and 900 mg a day as nicotinamide; this formula carries 16 mg as nicotinamide. CoQ10 is not counted this way yet: see its card above.
2 HOURS APART
Both carry 1,000 mg of vitamin C, and above 500 mg a dose vitamin C may break down B12. The evidence is weak and mostly from the lab, but the rule is conservative: those formulas are served at least two hours away from this one.
TALK TO A DOCTOR FIRST
It is excluded if you take a vitamin K antagonist such as warfarin or acenocoumarol, or have liver disease. Ask a doctor first if you are pregnant or breastfeeding, because the data on CoQ10 are limited. Ask a doctor first too if you take apixaban or dabigatran, take blood pressure medication, are in cancer treatment, take levodopa without carbidopa, isoniazid, cycloserine or anticonvulsants, or have gout, an active stomach ulcer, poorly controlled diabetes, peripheral neuropathy or polycythaemia vera. On metformin, a proton pump inhibitor or an H2 blocker such as famotidine long term, tell your doctor: all three can lower your B12. It is designed for healthy adults. Do not exceed the daily dose, do not use it in place of a varied diet, and keep it out of reach of young children. The app asks before it ever assigns this one.
WHERE THIS COMES FROM
Regulation (EU) 432/2012 on permitted health claims · Regulation (EU) 1169/2011 on nutrient reference values · EFSA Journal 2010;8(10):1793 on coenzyme Q10 · EFSA 2023 tolerable upper intake level for vitamin B6. Every line on this page is tied to one of the 810 sources on file, and 443 of the 9,730 possible ingredient pairs in our library are documented so far.
WHERE IT COMES FROM
Five sources hold up this formula: the regulation that lets us make the claims, the EFSA opinion behind its main claim, the EFSA opinion that rejected CoQ10, the reference intakes behind the % NRV column, and the upper limit we watch most closely.
Reviewed by VION nutrition team · last reviewed 16 September 2026
WHAT IS NOT PROVEN YET
This formula has not completed clinical validation. Six of its seven ingredients rest on an authorised EU claim at the dose used, and the seventh, CoQ10, on published work alone. The combination itself has not been tested by us in a trial. When it is, the result goes on this page, whatever it says.
YOU DO NOT PICK YOUR FORMULAS
The questionnaire and your first weeks of data decide which six of the 29 end up in your device. This page exists so you can read what one of them is before that happens.
Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition. Nothing here replaces a healthcare professional.
Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition.
