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D3 / K2
ADAPT BLOODWORKPENDING CLINICAL VALIDATION

D3 / K2

Three ingredients for when your blood test comes back low on vitamin D: more vitamin D3 than any other VION formula, with the vitamin K2 and magnesium our library pairs it with. It runs for 12 weeks and ends with a new test, not with a promise.

WHENNight, with dinner
WITH FOODYes, preferably. With your dinner
DOSE VOLUME0.4 ml, in two 0.2 ml pulses
INGREDIENTS3 active, 0 fillers
CARTRIDGE45 ml · up to 112 nights
SLOT1 of the 6 in your device
See if it is in your plan Back to the library

WHAT IS IN IT

Three actives. Nothing else.

These are the reference doses of the formula, at the full 0.4 ml. Your device pours in steps of 0.2 ml, so this one has only two steps, and the plan behind it is written for the full dose every night.

INGREDIENTFORMPER DOSE% NRVWHAT IT IS THERE FOR
Vitamin D3Cholecalciferol62.5 µg1,250%Maintenance of normal bones and normal absorption of calcium and phosphorus. The dose is set for a low blood result
Vitamin K2Menaquinone-7 (MK-7 trans)100 µg133%Maintenance of normal bones. Also the reason this formula is ruled out on warfarin
MagnesiumBisglycinate100 mg27%Maintenance of normal bones, the claim this formula is filed under
Total volume0.4 mlTwo pulses of 0.2 ml, the smallest step the device can serve
Vitamin D3Cholecalciferol62.5 µg1,250% NRV

Maintenance of normal bones and normal absorption of calcium and phosphorus. The dose is set for a low blood result

Vitamin K2Menaquinone-7 (MK-7 trans)100 µg133% NRV

Maintenance of normal bones. Also the reason this formula is ruled out on warfarin

MagnesiumBisglycinate100 mg27% NRV

Maintenance of normal bones, the claim this formula is filed under

Total volume 0.4 ml 

Two pulses of 0.2 ml, the smallest step the device can serve

No proprietary blends, no "complex" hiding the amounts, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.

No proprietary blends, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.

THE SCIENCE BEHIND IT

All three have an authorised claim. None of them is about your blood level.

In the EU, only a short list of health claims is authorised. Vitamin D, vitamin K and magnesium are all on it for normal bones. None of those claims says anything about raising your vitamin D level. The claims are what we are allowed to say. Your blood test is the reason this formula is on your plan.

Vitamin D3

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Vitamin D contributes to the maintenance of normal bones.”

Regulation (EU) 432/2012, on a product that is at least a source of vitamin D. The NRV is only 5 µg, so 62.5 µg reads as 1,250%. It is under the EFSA upper limit of 100 µg a day, but it is two and a half times the 25 µg in Bones & joints, and above the 20 µg the German BfR suggests for a supplement. It only goes out on a low blood result, for 12 weeks at a time and with a new test at the end.

Reg. 432/2012 · EFSA Journal 2009;7(9):1227 · UL 100 µg · 12 sources on file

Vitamin K2

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Vitamin K contributes to the maintenance of normal bones.”

Regulation (EU) 432/2012. 100 µg is 133% of the NRV. EFSA has set no upper limit for it; the German BfR reference for a supplement is 80 µg, which this formula passes, and we hold your whole plan to 360 µg. It has a second authorised claim, “Vitamin K contributes to normal blood clotting”. Vitamin K is involved in blood clotting, which is why this formula is ruled out on warfarin or acenocoumarol: our file records that it antagonises them directly, and a study on file saw doses as low as 10 µg a day change how some people respond to warfarin.

Reg. 432/2012 · EFSA Journal 2009;7(9):1228 · no EFSA upper limit · 8 sources on file

Magnesium

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Magnesium contributes to the maintenance of normal bones.”

Regulation (EU) 432/2012, on a product that is at least a source of magnesium, which means 15% of the NRV per dose. 100 mg is 27%. It is here because our library documents it as a cofactor in the steps that activate vitamin D, and records the pair as one to formulate together. 100 mg leaves room under the 250 mg upper limit, but not for a second formula at 150 mg or more.

Reg. 432/2012 · EFSA Journal 2009;7(9):1216 · NRV 375 mg · UL 250 mg · 14 sources on file

HOW IT IS POURED

Two pulses. Set by your blood test, not by last night.

The full dose of this formula is 0.4 ml, which the device serves as two pulses of 0.2 ml. For some formulas, your band decides how many. For this one, no wearable marker in our library moves the dose: the plan on file is 62.5 µg of vitamin D3 a day for 12 weeks, then a new test. One pulse on its own would also drop the magnesium to 50 mg, 13% of the NRV, below the 15% its claim needs.

TONIGHT'S POUR

12
0.4 ml of 0.4 mlset by your blood test, not your band

NIGHT, WITH DINNER

Why then

Our timing rules keep bisglycinate magnesium to the evening. The other two do not mind the hour much: the K2 stays in your blood for around three days, and vitamin D3 has no fixed hour in our file, though it notes some studies prefer the morning.

WITH YOUR DINNER

Why with food

Vitamin D3 and K2 dissolve in fat. Our reference file puts the gain in vitamin D3 absorption with a meal that has some fat in it at 32–50%. This formula rides on your dinner on purpose.

45 ML CARTRIDGE

How long it lasts

At 0.4 ml a night it is up to 112 nights. One 12-week cycle is 84, so a single cartridge covers the whole cycle.

HOW IT ENTERS YOUR PLAN

An ADAPT formula starts with a blood test. It ends with another.

ADAPT is the part of your plan that follows your bloodwork. It goes in when a result is out of range, runs for a fixed period at a fixed dose, and comes out when a new test says so.

  1. 01

    It starts with a blood result

    It is added when your 25-OH vitamin D comes back below 30 ng/ml, the bottom of the normal range in our biomarker library. Not from your questionnaire, not from your band.

  2. 02

    It runs for 12 weeks

    84 days at 62.5 µg of vitamin D3 a day, then a new 25-OH vitamin D test. Nothing about this formula moves inside that window.

  3. 03

    The next test decides what follows

    At 30 ng/ml or above, this formula comes out and Bones & joints takes over, with 25 µg of vitamin D3 a day to maintain it. Still below 30, the next step is a closer look at how you absorb it and at your parathyroid hormone (PTH), not simply another round.

  4. 04

    A 90-day pause before any second cycle

    If a second cycle is needed, 90 days pass between the two, and there are never more than two cycles in a year. No authority sets those two numbers. They are our own clinical decision, because a long repletion with no check can push blood calcium too high.

SAFETY AND INTERACTIONS

What it never shares a night with.

Every pair of ingredients in our library is checked against the others before a plan is built. Inside this formula, all three pairs are documented, and all three as complementary. This is what the check rules out.

COUNTED TOGETHER

Bones & joints

That formula carries 200 mg of magnesium at night. With the 100 mg here you would reach 300 mg, past the 250 mg upper limit for supplemental magnesium, so the engine will not run the two together. Bones & joints comes after this one, not alongside it. The same count rules out the other seven VION formulas that carry 150 to 200 mg of magnesium.

UPPER LIMIT TRACKED

Autoimmune thyroid · Low testosterone

Both carry 50 µg of vitamin D3. With the 62.5 µg here you would reach 112.5 µg, past the EFSA upper limit of 100 µg a day. The engine adds up your vitamin D across every formula and blocks any addition that would take it over. One of our 25 µg formulas fits next to this one. Two do not.

TALK TO A DOCTOR FIRST

Not for everyone

Ruled out if you take a vitamin K antagonist such as warfarin, acenocoumarol or phenprocoumon, for any reason, including a mechanical heart valve or an active clotting disorder; if you have high blood calcium; or if you have sarcoidosis. Talk to a doctor first if you have primary hyperparathyroidism, lymphoma or granulomatous tuberculosis, calcium kidney stones, kidney disease (magnesium is ruled out in advanced kidney disease), liver disease, a heart rhythm problem, heart block or a slow heart rate, myasthenia gravis or histamine intolerance; if you have cancer or are in cancer treatment; if you are pregnant or breastfeeding; if you are under 18, where the upper limits are lower; or if you take other anticoagulants such as apixaban, antiplatelets, digoxin, diuretics, steroids, statins, anti-epileptics (phenytoin, phenobarbital, carbamazepine), orlistat, cholestyramine or colestipol, long antibiotic courses, aminoglycosides or amphotericin B, acid reducers (PPIs), calcium channel blockers, benzodiazepines or other sedatives, magnesium-containing antacids or laxatives, muscle relaxants used in surgery, bisphosphonates, tetracycline antibiotics (at least 2 hours apart), quinolone antibiotics (take them 2 hours before, or 4 to 6 hours after, this formula) or levothyroxine (4 hours apart). Keep it apart from an iron formula as well: our file recommends a light separation from iron doses of 25 mg or more, and Iron carries 28 mg. Its vitamin K2 is usually made from soy: check with us if you are allergic to soy. Neither the D3 nor the K2 is vegan. The app asks before it ever assigns this one.

WHERE THIS COMES FROM

Regulation (EU) 432/2012 on permitted health claims · Regulation (EU) 1169/2011 on nutrient reference values · EFSA Journal 2009;7(9):1227 on vitamin D and bones · EFSA tolerable upper intake levels for vitamin D and supplemental magnesium · BfR maximum levels for vitamins in food supplements. Every line on this page is tied to one of the 810 sources on file, and 443 of the 9,730 possible ingredient pairs in our library are documented so far.

WHERE IT COMES FROM

You can check every line of this page.

Six sources hold up this formula: the regulation that lets us make the bone claims, the reference values we measure against, the EFSA opinion behind the vitamin D claim, the upper limits we stay under, the stricter German references we do not, and the trial behind pairing vitamin D3 with K2.

REGULATIONRegulation (EU) 432/2012 — list of permitted health claims made on foodsbone claims for vitamin D, vitamin K and magnesium
NRVRegulation (EU) 1169/2011, Annex XIII Part A — nutrient reference valuesthe 1,250%, 133% and 27% above
EFSAEFSA Journal 2009;7(9):1227 — opinion on vitamin D and bones, calcium absorption and immune functionbehind the vitamin D bone claim
EFSA ULTolerable upper intake levels — vitamin D 100 µg (EFSA Journal 2023, 10.2903/j.efsa.2023.8145) and supplemental magnesium 250 mg per daywe serve 62.5 µg and 100 mg
BfRBfR-Wissenschaft 03/2018 — Höchstmengenvorschläge für Vitamine und Mineralstoffe in Nahrungsergänzungsmittelnvitamin D 20 µg and vitamin K 80 µg: this formula is above both
TRIALKnapen et al. Osteoporosis International 2013 — three-year low-dose menaquinone-7 supplementation and bone loss in healthy postmenopausal womenused 180 µg of MK-7; this formula carries 100 µg

Reviewed by VION nutrition team · last reviewed 16 September 2026

WHAT IS NOT PROVEN YET

This formula has not completed clinical validation. Its three ingredients carry authorised EU claims for normal bones, but none of those claims is about raising your vitamin D level, and the 12-week plan has not been tested by us in a trial. The 90-day pause and the two-cycle limit are our own clinical decisions. When the plan is tested, the result goes on this page, whatever it says.

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YOU DO NOT PICK YOUR FORMULAS

Your data does.

The questionnaire and your first weeks of data decide which six of the 29 end up in your device. This page exists so you can read what one of them is before that happens.

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Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition. Nothing here replaces a healthcare professional.

Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition.