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Digestion & microbiome
CORE DIGESTIONPENDING CLINICAL VALIDATION

Digestion & microbiome

Three bacterial strains, two prebiotic fibres and a small dose of zinc, taken before breakfast. It is a base formula for your gut, held for weeks rather than changed day to day, and only one line on this page is an authorised claim.

WHENMorning, 15–30 min before breakfast
WITH FOODNo. Before breakfast, on an empty stomach
DOSE VOLUME4.2 ml, in twenty-one 0.2 ml pulses
INGREDIENTS6 active, 0 fillers
CARTRIDGE45 ml · up to 10 mornings
SLOT1 of the 6 in your device

WHAT IS IN IT

Six actives. Nothing else.

These are the reference doses of the formula. Your device pours them in steps of 0.2 ml, so any adjustment to what you take moves in whole pulses, never in fractions of one.

INGREDIENTFORMPER DOSE% NRVWHAT IT IS THERE FOR
Lactobacillus acidophilusStrain NCFM5 billion CFU—Probiotic strain. On EFSA's safety list, with no authorised claim
Bifidobacterium lactisStrain Bl-045 billion CFU—Probiotic strain. On EFSA's safety list, with no authorised claim
Akkermansia muciniphilaPasteurised, strain MucT10 billion CFU—EU novel food, authorised up to 3.4 billion cells a day in adults. This dose is above that and flagged for review
InulinChicory (Cichorium intybus)3,000 mg—Prebiotic fibre. Its authorised claim needs 12 g a day, so it does not apply here
Galactooligosaccharides (GOS)—2,000 mg—Prebiotic fibre. EFSA rejected the claims made for it
ZincBisglycinate5 mg50%Normal protein synthesis
Total volume4.2 mlTwenty-one pulses of 0.2 ml, the smallest step the device can serve
Lactobacillus acidophilusStrain NCFM5 billion CFU—

Probiotic strain. On EFSA's safety list, with no authorised claim

Bifidobacterium lactisStrain Bl-045 billion CFU—

Probiotic strain. On EFSA's safety list, with no authorised claim

Akkermansia muciniphilaPasteurised, strain MucT10 billion CFU—

EU novel food, authorised up to 3.4 billion cells a day in adults. This dose is above that and flagged for review

InulinChicory (Cichorium intybus)3,000 mg—

Prebiotic fibre. Its authorised claim needs 12 g a day, so it does not apply here

Galactooligosaccharides (GOS)—2,000 mg—

Prebiotic fibre. EFSA rejected the claims made for it

ZincBisglycinate5 mg50% NRV

Normal protein synthesis

Total volume 4.2 ml 

Twenty-one pulses of 0.2 ml, the smallest step the device can serve

No proprietary blends, no "complex" hiding the amounts, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.

No proprietary blends, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.

THE SCIENCE BEHIND IT

Only one of these six has an authorised claim at this dose.

In the EU, only a short list of health claims is authorised. Two of our six ingredients have one, but inulin's needs four times the amount this formula carries, so we do not use it. The three bacteria rest on safety approvals, which say they are considered safe to take, not what they do for you, and the Akkermansia dose here sits above the level its approval sets.

Lactobacillus acidophilus

NO AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

Nothing. We are not allowed to attribute an effect to it, so we do not.

Strain NCFM. The species is on EFSA's QPS list, the qualified presumption of safety for microorganisms used in food. That tells you it is considered safe to take. It does not let us promise anything about your gut.

EFSA QPS list 2024 · 1 source on file · not a claim

Bifidobacterium lactis

NO AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

Nothing. We are not allowed to attribute an effect to it, so we do not.

Strain Bl-04, listed by EFSA as Bifidobacterium animalis subsp. lactis on the same QPS safety list. A safety status, not a claim. Strains like this are typically grown on dairy, which is why milk allergy and lactose intolerance are on the warning list below.

EFSA QPS list 2024 · 1 source on file · not a claim

Akkermansia muciniphila

NO AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

Nothing. Its EU authorisation covers safety, not an effect.

Pasteurised Akkermansia muciniphila was assessed by EFSA and authorised in the EU as a novel food in 2021, for up to 3.4 billion cells a day in adults. That limit is written in cells, because pasteurised bacteria are not alive; our composition table records this ingredient in CFU, the unit we use for the two live strains. The reference dose in this formula is 10 billion, about three times that maximum, so we do not present the authorisation as covering it: the dose is flagged for clinical and regulatory review. And even within the limit, a novel food authorisation is permission to sell it as a food, not permission to say what it does for you, so we do not.

EFSA Journal 2021;19(9):6780 · up to 3.4 billion cells a day · 2 sources on file · not a claim

Inulin

NO AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

Not at this dose. The authorised claim needs 12 g a day, and this formula carries 3 g.

Native chicory inulin does have an authorised EU claim on bowel function, but only at 12 g a day. We did not raise the dose to reach it, and we will not borrow the claim at a quarter of it. It is here as a prebiotic fibre alongside the bacteria.

EFSA Journal 2015;13(1):3951 · 9 sources on file · claim not applicable

Galactooligosaccharides (GOS)

NO AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

Nothing. EFSA looked at the claims made for GOS and rejected them.

The claims submitted for GOS on digestive discomfort and on pathogens were rejected, and GOS is not on the authorised list. It is included as a second prebiotic fibre, and its dose is the first thing reviewed if this formula leaves you bloated.

EFSA Journal 2011;9(6):2060 · 2 sources on file · claim rejected

Zinc

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Zinc contributes to normal protein synthesis.”

Regulation (EU) 432/2012, which only allows the claim on a product that is at least a source of zinc. This formula carries 5 mg, 50% of the NRV, and stays well under the 25 mg upper limit.

Reg. 432/2012 · EFSA Journal 2010;8(10):1819 · NRV 10 mg · 14 sources on file

HOW IT IS POURED

Twenty-one pulses. For now, all twenty-one.

The full dose of this formula is 4.2 ml, which the device serves as twenty-one pulses of 0.2 ml. It can pour less in 0.2 ml steps, but a night-by-night change needs a signal to follow, and no wearable or blood marker has been linked to this formula yet. Until one is, nothing from your band moves it, and we would rather tell you that than show you a number that changes for no reason.

TONIGHT'S POUR

123456789101112131415161718192021
4.2 ml of 4.2 mlno wearable or blood marker is tied to this formula yet

MORNING, 15–30 MIN BEFORE BREAKFAST

Why then

The bacteria and the fibres that feed them are meant to reach an empty stomach, where more of them survive the stomach acid on the way through. Fifteen to thirty minutes before breakfast is the window that gives them that.

BEFORE YOUR MEAL

Why not with breakfast

Food in the stomach is exactly what this timing avoids. Zinc also absorbs better away from meals, since a diet rich in phytates from cereals and pulses can cut its absorption by around half.

45 ML CARTRIDGE

How long it lasts

At the full 4.2 ml it is 10 mornings. At a partial pour it lasts longer, so the app orders your refill from what you actually took.

HOW IT ENTERS YOUR PLAN

A CORE formula is not suggested. It is assigned.

CORE is the part of your plan that stays still on purpose. It comes out of your questionnaire, not out of last night's data, and this one is held long enough for a change in your gut to actually mean something.

  1. 01

    It comes from your questionnaire

    Choosing digestive health among your goals, together with the rest of your answers, is what puts this formula in your base. No wearable data is needed for that first decision.

  2. 02

    It is held for at least 8 weeks

    Trials on these strains looked for stable changes in the microbiome over 6 to 12 weeks, and 8 weeks is the figure we work to. Nothing about the recipe moves inside that window.

  3. 03

    It is reviewed at 8 weeks

    Your digestive symptoms are reassessed. If bloating or wind persists, the GOS dose is the first thing looked at. If SIBO is diagnosed, this formula comes out and a different one takes its slot.

  4. 04

    There is no built-in break

    No official source sets a washout period or a yearly limit for these ingredients, so the formula has no forced pause. It stays in your base for as long as the goal behind it does.

SAFETY AND INTERACTIONS

What it is checked against.

Every pair of ingredients in our library is checked against the others before a plan is built. For this formula, zinc is counted across your whole plan, the two fibres are counted within the formula, and some people should not take it at all.

COUNTED ACROSS YOUR PLAN

Zinc in Immunity, Skin, hair & nails and others

Zinc also sits in Immunity and Skin, hair & nails at 10 mg each, and in several BOOST and ADAPT formulas. The EFSA upper limit of 25 mg a day counts everything you take, so the engine adds the formulas up and will not add one that takes you over it. From 15 mg a day of zinc, copper has to come with it.

COUNTED WITHIN THIS FORMULA

Inulin and GOS

Both are fermentable fibres. Our inulin record lists GOS as a second fermentable fibre that can double up with it, and caps total fermentable fibre at 10–15 g a day, the range most people tolerate without symptoms. This formula carries 5 g. For inulin on its own, the tolerance reference is 10 g a day, not a formally established EFSA upper limit, and this formula carries 3 g. No other VION formula carries fermentable fibre today.

TALK TO A DOCTOR FIRST

Not for everyone

Do not take it if you have SIBO (small intestinal bacterial overgrowth) or severe immunosuppression. Ask a doctor first if you are immunocompromised, on chemotherapy or any cancer treatment, have a central venous catheter, or have had recent abdominal surgery. Not for galactosaemia (the GOS carries residual lactose), hereditary fructose intolerance or a low-FODMAP diet; with IBS or FODMAP sensitivity, start low, as wind is common at first, and inulin above 15–20 g a day can cause diarrhoea. It contains milk-derived ingredients, so it is not for milk allergy, lactose intolerance or a vegan diet, and it does not fit a keto diet. Take care with an allergy to chicory or ragweed. Not for children under 3 without medical supervision. Avoid intranasal zinc products, and ask first if you have lost your sense of smell before, have haemochromatosis or Menkes disease, or take zinc at 40 mg a day or more without copper. If you take quinolone antibiotics, take them at least 2 h before or 4–6 h after this formula. Keep it at least 2 h apart from tetracyclines, 1 h from penicillamine, 30 min from bisphosphonates and 1–2 h from a broad-spectrum antibiotic course. Keep it at least 2 h apart from iron at 25 mg a day or more — the Iron formula carries 28 mg in the same morning window — and from calcium at 500 mg or more, from supplements or dairy. On thiazide diuretics, your zinc may need monitoring. On immunosuppressants, ask your doctor first. And the usual three: do not exceed the daily dose, it does not replace a varied and balanced diet, and keep it out of reach of young children.

WHERE THIS COMES FROM

Regulation (EU) 432/2012 on permitted health claims · EFSA Journal 2015;13(1):3951 on native chicory inulin · EFSA Journal 2011;9(6):2060 on galacto-oligosaccharides · EFSA Journal 2021;19(9):6780 on pasteurised Akkermansia muciniphila · EFSA QPS list for the two probiotic strains · EFSA tolerable upper intake level for zinc. Every line on this page is tied to one of the 810 sources on file, and 443 of the 9,730 possible ingredient pairs in our library are documented so far.

WHERE IT COMES FROM

You can check every line of this page.

Seven sources hold up this formula: the regulation that lets us make the zinc claim, the EFSA opinions on inulin and GOS, the novel food opinion on Akkermansia, the safety list for the two probiotic strains, the reference value behind the 50%, and the upper limit we stay under.

REGULATIONRegulation (EU) 432/2012 — list of permitted health claims made on foodsclaim for zinc · amended by Reg. (EU) 2015/2314 for native chicory inulin (12 g condition, not met) · GOS not included
EFSAEFSA Journal 2015;13(1):3951 — opinion on native chicory inulin and normal bowel functionsets the 12 g condition, not met here
EFSAEFSA Journal 2011;9(6):2060 — opinion on galacto-oligosaccharides (GOS)claims rejected
NOVEL FOODEFSA Journal 2021;19(9):6780 — safety of pasteurised Akkermansia muciniphila as a novel food under Regulation (EU) 2015/2283safety assessment, not a claim · up to 3.4 billion cells a day in adults; this dose is above it
EFSA QPSEFSA Qualified Presumption of Safety (QPS) list, 2024 — Lactobacillus acidophilus and Bifidobacterium animalis subsp. lactissafety status, not a claim
NRVRegulation (EU) 1169/2011, Annex XIII — nutrient reference value for zinc, 10 mg5 mg is 50%
EFSA ULTolerable upper intake level for zinc — 25 mg per daywe serve 5 mg

Reviewed by VION nutrition team · last reviewed 16 September 2026

WHAT IS NOT PROVEN YET

This formula has not completed clinical validation. Its six ingredients rest on published work, on EU safety approvals and, in the case of zinc, on an authorised claim, but the combination itself has not been tested by us in a trial. When it is, the result goes on this page, whatever it says.

YOU DO NOT PICK YOUR FORMULAS

Your data does.

The questionnaire and your first weeks of data decide which six of the 29 end up in your device. This page exists so you can read what one of them is before that happens.

Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition. Nothing here replaces a healthcare professional.

Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition.