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Skin, hair & nails
CORE HEALTHY AGINGPENDING CLINICAL VALIDATION

Skin, hair & nails

Six ingredients for the upkeep of normal hair, skin and nails. Three of them carry an authorised EU claim for exactly that. The other three are here on published work, not on a claim. It is a base formula you keep for months, not a quick fix.

WHENMorning, with breakfast
WITH FOODYes, preferably. With your breakfast
DOSE VOLUME0.6 ml, in three 0.2 ml pulses
INGREDIENTS6 active, 0 fillers
CARTRIDGE45 ml · up to 75 mornings
SLOT1 of the 6 in your device
See if it is in your plan Back to the library

WHAT IS IN IT

Six actives. Nothing else.

These are the reference doses of the formula. Your device pours them in steps of 0.2 ml, so what you actually take on a given morning can sit below the reference when your data does not call for the full dose.

INGREDIENTFORMPER DOSE% NRVWHAT IT IS THERE FOR
BiotinD-biotin100 µg200%Maintenance of normal hair and normal skin
Vitamin CL-ascorbic acid or magnesium ascorbate80 mg100%Normal collagen formation for the normal function of skin
ZincBisglycinate10 mg100%Maintenance of normal hair, normal nails and normal skin
SiliconCholine-stabilised orthosilicic acid (ch-OSA)10 mg—Included for its part in forming collagen. Its EU claims were rejected
Hydrolysed collagenType I + III peptides10 g—Skin support on published reviews. It has no EU claim of its own
Hyaluronic acidLow molecular weight (50–300 kDa)100 mg—Skin hydration on small published trials. Its EU claims were rejected
Total volume0.6 mlThree pulses of 0.2 ml, the smallest step the device can serve
BiotinD-biotin100 µg200% NRV

Maintenance of normal hair and normal skin

Vitamin CL-ascorbic acid or magnesium ascorbate80 mg100% NRV

Normal collagen formation for the normal function of skin

ZincBisglycinate10 mg100% NRV

Maintenance of normal hair, normal nails and normal skin

SiliconCholine-stabilised orthosilicic acid (ch-OSA)10 mg—

Included for its part in forming collagen. Its EU claims were rejected

Hydrolysed collagenType I + III peptides10 g—

Skin support on published reviews. It has no EU claim of its own

Hyaluronic acidLow molecular weight (50–300 kDa)100 mg—

Skin hydration on small published trials. Its EU claims were rejected

Total volume 0.6 ml 

Three pulses of 0.2 ml, the smallest step the device can serve

No proprietary blends, no "complex" hiding the amounts, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.

No proprietary blends, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.

THE SCIENCE BEHIND IT

Three of these six have an authorised claim. Three do not.

In the EU, only a short list of health claims is authorised. Three of the ingredients here are on it for hair, skin or nails. The other three are not: EFSA assessed claims for each of them and rejected them. We would rather show you that than write a sentence that sounds the same for all six.

Biotin

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Biotin contributes to the maintenance of normal hair.”

Regulation (EU) 432/2012, on a product that is at least a source of biotin. 100 µg is 200% of the NRV. Its sister claim, “Biotin contributes to the maintenance of normal skin”, rests on the same regulation. There is no EFSA upper limit for biotin; the German BfR proposes 180 µg in supplements, and this formula stays under it.

Reg. 432/2012 · EFSA Journal 2009;7(9):1209 · NRV 50 µg · 9 sources on file

Vitamin C

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Vitamin C contributes to normal collagen formation for the normal function of skin.”

Regulation (EU) 432/2012, on a product that is at least a source of vitamin C. 80 mg is 100% of the NRV. It is the only ingredient here that can carry a collagen claim: the collagen itself cannot. Our library asks for at least 80 mg of vitamin C whenever collagen goes into a plan, which is exactly what this formula carries.

Reg. 432/2012 · EFSA Journal 2009;7(9):1226 · NRV 80 mg · 11 sources on file

Zinc

AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

“Zinc contributes to the maintenance of normal nails.”

Regulation (EU) 432/2012, on a product that is at least a source of zinc. It is the only ingredient here with a claim for nails, and it carries the ones for “normal hair” and “normal skin” too. 10 mg is 100% of the NRV and 40% of the 25 mg daily upper limit EFSA sets. The German BfR proposes a lower ceiling of 6.5 mg for supplements, so our 10 mg sits above that proposal and inside the EFSA limit the engine applies.

Reg. 432/2012 · EFSA Journal 2010;8(10):1819 · NRV 10 mg · UL 25 mg · 14 sources on file

Silicon

NO AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

Nothing. EFSA assessed claims for it on collagen, bones, hair and skin, and rejected them.

It is here for the part silicon plays in forming collagen, which EFSA did not find proven enough for a claim. It comes in the choline-stabilised form EFSA assessed as a source of silicon. 10 mg is the maximum the German BfR proposes for supplements, in the absence of an EFSA upper limit. This formula sits on that line, not over it.

EFSA Journal 2011;9(6):2259 · BfR maximum 10 mg · 2 sources on file · claims rejected

Hydrolysed collagen

NO AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

Nothing of its own. The collagen claim on this page belongs to vitamin C.

EFSA rejected the skin and joint claims submitted for collagen. It stays in on the published skin work on file, including a systematic review of oral collagen for the skin. 10 g sits at the top of the 2.5–10 g a day used in that work. That is a reason to include it, not a permission to promise anything. It is animal-derived.

5 sources on file · 1 with a PMID · no claim of its own

Hyaluronic acid

NO AUTHORISED CLAIM

WHAT WE ARE ALLOWED TO SAY

Nothing. EFSA assessed claims for it on joints and on skin, and rejected both.

Our file rests it on small trials of oral hyaluronic acid, mostly at 80–240 mg a day, and 100 mg sits inside that range. Whether it works when taken by mouth is still debated, and our own confidence in it is the lowest of the six. We would rather tell you that than dress it up.

EFSA Journal 2009;7(9):1266 · 7 sources on file · 0 with a PMID · claims rejected

HOW IT IS POURED

Three pulses. For now, always three.

The full dose of this formula is 0.6 ml, which the device serves as three pulses of 0.2 ml. It can pour less in 0.2 ml steps, but a morning-by-morning change needs a signal to follow, and no wearable or blood marker has been linked to this formula yet. Until one is, nothing from your band moves it, and we would rather tell you that than show you a number that changes for no reason.

TONIGHT'S POUR

123
0.6 ml of 0.6 mlno wearable or blood marker is tied to this formula yet

MORNING, WITH BREAKFAST

Why then

Our clinical note ties this formula to breakfast, where the collagen, the hyaluronic acid and the vitamin C that collagen needs are served together. The morning also suits the biotin. If you have a blood test coming up, biotin is the one thing to plan around: stop it 72 hours before.

WITH YOUR BREAKFAST

Why with food

Preferably, not strictly. Vitamin C is gentler on the stomach with a meal, and the collagen and hyaluronic acid work with or without one. Zinc absorbs better away from food, and a meal heavy in wholegrains or pulses can cut its absorption by around half, which is why this is a preference and not a rule.

45 ML CARTRIDGE

How long it lasts

At the full 0.6 ml it is 75 mornings. At a partial pour it would last longer, so the app orders your refill from what you actually took.

HOW IT ENTERS YOUR PLAN

A CORE formula is not suggested. It is assigned.

CORE is the part of your plan that stays still on purpose. It comes out of your questionnaire, not out of last night's data, and it is held long enough for a change to actually mean something. For hair, skin and nails, that means months, not weeks.

  1. 01

    It comes from your questionnaire

    Choosing skin, hair and nails as one of your goals is what puts this formula in the running for your base. Your answers on health conditions and regular medication decide whether it can go in at all, and it never does if you take a vitamin K antagonist such as warfarin. No wearable data is needed for that first decision.

  2. 02

    It is held for at least 21 days

    Long enough for a change to be a signal rather than noise. Nothing about this formula moves inside that window. The reference course in our library is 90 days, because a hair follicle takes around three months to renew.

  3. 03

    It is reviewed at 90 days

    If nothing has changed by then and you took it regularly, the next step is to look for other causes, such as low ferritin, an underactive thyroid or low vitamin D. That is VION's own clinical rule, not a regulatory one.

  4. 04

    There is no built-in break

    No official source sets a washout period or a yearly limit for these ingredients, so the formula has no forced pause. It stays in your base for as long as the goal behind it does. If your answers change at your next review, you are told before it comes out.

SAFETY AND INTERACTIONS

What it never shares a morning with.

Every pair of ingredients in our library is checked against the others before a plan is built. This is what that check rules out for this formula.

UPPER LIMIT TRACKED

Acute immunity · Cold symptom support

Both BOOST formulas carry 15 mg of zinc. Next to the 10 mg here that would come to 25 mg, the EFSA upper limit, which counts everything you take. Zinc also sits in Immunity, Digestion & microbiome and several ADAPT formulas, so the engine adds up every formula you are on and blocks any combination that reaches or passes that limit. Both of those BOOST formulas also carry 1,000 mg of vitamin C; with the 80 mg here that goes past the 1,000 mg our library allows across two active formulas. From 15 mg a day of zinc taken for long, our library asks for 1 mg of copper alongside it.

COUNTED TOGETHER

Daily athletic

That BOOST formula also carries 10 g of hydrolysed collagen, in the same morning window. There is no official upper limit for collagen, but our library treats 15 g a day across formulas as a sensible ceiling, because of the protein load. The two together would come to 20 g, above that ceiling.

TALK TO A DOCTOR FIRST

Not for everyone

Ruled out if you take a vitamin K antagonist such as warfarin or acenocoumarol. Ask a doctor first if you take other anticoagulants (apixaban, dabigatran); are pregnant or breastfeeding, or under 18; have a thyroid condition or heart disease; have chronic kidney disease, kidney stones or severe kidney failure; have severe liver disease on a protein-restricted diet; have haemochromatosis, thalassaemia or other iron overload, G6PD deficiency or Menkes disease; or have, or have had, cancer, or are on any cancer treatment. The biotin can distort blood tests such as TSH, troponin, hCG and vitamin D: stop it at least 72 hours before any blood test and tell the laboratory, and if a heart attack is ever suspected, tell the team treating you, as a troponin result can read falsely low. Because of that FDA-identified risk, check with your doctor before you start this one at all. Ask a doctor first, too, if you take deferoxamine, anticonvulsants (carbamazepine, phenytoin, phenobarbital, primidone), cisplatin or other chemotherapy, immunosuppressants, thiazide diuretics or ACE inhibitors, statins with niacin, oral contraceptives, isotretinoin or a long course of antibiotics: for these, moving the doses apart does not answer the problem. What you do keep apart from the zinc is quinolone antibiotics (2 hours before it or 4–6 hours after), tetracyclines (at least 2 hours), penicillamine (at least 1 hour), bisphosphonates (at least 30 minutes) and antacids (especially aluminium-based ones); and do not take levothyroxine at the same time as the collagen. The collagen is animal-derived (bovine, porcine, marine or avian): not for fish or egg allergies, not vegan or vegetarian, and halal or kosher only with specific certification. Avoid intranasal zinc products, and ask first if you have lost your sense of smell before or take zinc at 40 mg a day or more without copper. And the usual three: do not exceed the daily dose, it does not replace a varied and balanced diet, and keep it out of reach of young children. The app asks before it ever assigns this one.

WHERE THIS COMES FROM

Regulation (EU) 432/2012 on permitted health claims · Regulation (EU) 1169/2011 on nutrient reference values · EFSA tolerable upper intake level for zinc · FDA safety communication on biotin and lab tests · EFSA Journal 2011;9(6):2259 on silicon. Every line on this page is tied to one of the 810 sources on file, and 443 of the 9,730 possible ingredient pairs in our library are documented so far.

WHERE IT COMES FROM

You can check every line of this page.

Eight sources hold up this formula: the regulation that lets us make the hair, skin and nail claims, the one that sets the reference values we measure against, the EFSA upper limit for zinc that we stay under, the German BfR list of proposed maximums that we stay under for silicon and biotin and go over for zinc, the two EFSA opinions that rejected claims for silicon and hyaluronic acid, the FDA warning behind the blood-test advice, and the review behind the collagen.

REGULATIONRegulation (EU) 432/2012 — list of permitted health claims made on foodsclaims for biotin, vitamin C and zinc · silicon, collagen and hyaluronic acid not included
NRVRegulation (EU) 1169/2011, Annex XIII Part A — nutrient reference valuesthe 200%, 100% and 100% above
EFSA ULTolerable upper intake level for zinc — 25 mg per day (EFSA, 2006)we serve 10 mg
BfRBfR-Wissenschaft 03/2018 — proposed maximum levels for vitamins and minerals in food supplementssilicon 10 mg, biotin 180 µg and zinc 6.5 mg; we serve 10 mg, 100 µg and 10 mg, so the zinc is above the BfR proposal and within the EFSA 25 mg limit
EFSAEFSA Journal 2011;9(6):2259 — scientific opinion on silicon and bone, hair, skin and collagenclaims rejected
EFSAEFSA Journal 2009;7(9):1266 and 2012;10(7):2806 — scientific opinions on hyaluronic acid, joints and skinclaims rejected
FDAFDA safety communication, 2019 — biotin may interfere with lab testswhy you stop it 72 hours before a blood test
REVIEWChoi, Sung, Juhasz, Mesinkovska. Journal of Drugs in Dermatology 2019 — oral collagen supplementation, a systematic review of dermatological applicationsPMID 30681787

Reviewed by VION nutrition team · last reviewed 16 September 2026

WHAT IS NOT PROVEN YET

This formula has not completed clinical validation. Its six ingredients rest on published work and, in three cases, on an authorised EU claim, but the combination itself has not been tested by us in a trial. When it is, the result goes on this page, whatever it says.

Others in the same area

See all 29 formulas  →
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YOU DO NOT PICK YOUR FORMULAS

Your data does.

The questionnaire and your first weeks of data decide which six of the 29 end up in your device. This page exists so you can read what one of them is before that happens.

Become a founder · €249 Back to the library

Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition. Nothing here replaces a healthcare professional.

Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition.