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Four fat-soluble ingredients, taken with your dinner: the omega-3s behind an authorised claim on normal heart function, vitamin K2, coenzyme Q10 and an olive polyphenol. It is a base formula, not a fix, and it is ruled out if you take a vitamin K antagonist: warfarin, acenocoumarol or phenprocoumon.
WHAT IS IN IT
These are the reference doses of the formula. Your device pours them in steps of 0.2 ml, so what you actually take on a given night can sit below the reference when your data does not call for the full dose.
Normal function of the heart, from 250 mg a day
Normal blood clotting. Also the reason this formula is ruled out on a vitamin K antagonist
Included on published evidence. Every EU claim for it was rejected
Included on published evidence. The olive-oil claim does not cover an extract
Nine pulses of 0.2 ml, the smallest step the device can serve
No proprietary blends, no "complex" hiding the amounts, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.
No proprietary blends, no bulking agents. If an ingredient is in the bottle it is in this table, with its form and its dose.
THE SCIENCE BEHIND IT
In the EU, only a short list of health claims is authorised. Two of the ingredients here are on it. Coenzyme Q10 had its claims looked at and rejected. The olive extract sits next to a claim that is authorised for olive oil only, so it does not cover this one. We would rather tell you that than write a sentence that sounds the same for all four.
WHAT WE ARE ALLOWED TO SAY
“EPA and DHA contribute to the normal function of the heart.”
Regulation (EU) 432/2012, for a daily intake of 250 mg. This formula carries 1,500 mg, in triglyceride or phospholipid form rather than ethyl ester. The same regulation holds a second omega-3 claim that needs 3 g a day. We do not reach that, so we do not make it.
Reg. 432/2012 · 250 mg a day minimum · 2 sources on file · 2 with a PMID
WHAT WE ARE ALLOWED TO SAY
“Vitamin K contributes to normal blood clotting.”
Regulation (EU) 432/2012, for products that are at least a source of vitamin K. This formula carries 75 µg as MK-7, which is 100% of the NRV. That same role in clotting is why it is never assigned to anyone on a vitamin K antagonist: warfarin, acenocoumarol or phenprocoumon.
Reg. 432/2012 · EFSA Journal 2009;7(9):1228 · NRV 75 µg · 8 sources on file
WHAT WE ARE ALLOWED TO SAY
Nothing. EFSA rejected every claim put to it, so we make none.
It is here on published work, not on a claim. That is a reason to include it, not a permission to promise anything. There is no EFSA upper limit. The one our database applies is the German BfR reference of 100 mg a day, and this formula serves 200 mg, twice that. 200 mg matches the French ANSES reference and is the total our own rule allows across your plan, but it is our rule, not an upper limit, and that dose is still pending clinical review.
EFSA Journal 2010;8(10):1793 · 9 sources on file · 1 with a PMID · not a claim
WHAT WE ARE ALLOWED TO SAY
None that applies here. The EU claim for olive polyphenols covers olive oil, not an extract.
Regulation (EU) 432/2012 authorises that claim only for olive oil with at least 5 mg of hydroxytyrosol and its derivatives per 20 g, with the benefit tied to 20 g of that oil a day. This formula carries 25 mg from an olive leaf extract with at least 40% hydroxytyrosol. That is not olive oil, so we cannot make the claim for it. It is here on published work, and that is a reason to include it, not a permission to promise anything. No upper limit has been set for it.
Reg. 432/2012 (olive oil only) · EFSA novel food opinion 2017 · 2 sources on file · not a claim
HOW IT IS POURED
The full dose of this formula is 1.8 ml, which the device serves as nine pulses of 0.2 ml. On a night when your band says you do not need the whole thing, it pours fewer and tells you why. From two pulses up, the EPA + DHA still clears the 250 mg its claim asks for. One pulse on its own would not.
TONIGHT'S POUR
NIGHT, WITH YOUR DINNER
All four dissolve in fat, and they need the fat of a meal to be taken up. Taking the omega-3s with food also cuts down the reflux they can cause on an empty stomach.
COENZYME Q10 AT NIGHT
Our reference file notes that some people sleep worse when coenzyme Q10 is taken late, and would place it earlier in the day. The same file suggests splitting any dose above 100 mg in two, and here 200 mg comes in one evening dose. It sits at dinner for the fat it needs. Both points are part of what clinical validation still has to settle.
45 ML CARTRIDGE
At the full 1.8 ml it is 25 nights. At a partial pour it lasts longer, so the app orders your refill from what you actually took.
HOW IT ENTERS YOUR PLAN
CORE is the part of your plan that stays still on purpose. It comes out of your questionnaire, not out of last night's data, and it is held long enough for a change to actually mean something.
Your answers, including your current medication, put this formula in your base. If you take a vitamin K antagonist (warfarin, acenocoumarol, phenprocoumon), it never gets that far. No wearable data is needed for that first decision.
Long enough for your own band to form and for a change to be a signal rather than noise. Nothing about this formula moves inside that window. After that, our file describes this as continuous, open-ended use, and also carries a cycle option of 24 weeks with a 4-week pause, at most twice a year. The two do not agree yet; that part is still pending clinical review.
Once it is in, the engine adjusts how much of the 1.8 ml you get, in 0.2 ml steps, from your resting heart rate and HRV of the last few days. The recipe itself does not change.
Your LDL, HDL and triglycerides are looked at again after 12 weeks. If your LDL has not responded after three months, the Oxidative cardiovascular formula (currently being reformulated) is added or takes its place. That formula repeats the same three actives at the same time of day: 200 mg of coenzyme Q10, 1,500 mg of EPA + DHA and 25 mg of olive hydroxytyrosol. Added on top of this one it would double all three and take coenzyme Q10 to 400 mg, twice the 200 mg daily total our own rule allows, so only the swap stays inside that rule. Our file holds both options open and does not say which one wins. If you start anticoagulant treatment, this one is reformulated without vitamin K2.
SAFETY AND INTERACTIONS
Every pair of ingredients in our library is checked against the others before a plan is built. Inside this formula, the one documented pair, coenzyme Q10 with vitamin K2, needs no separation. Vitamin K2 is also in Bones & joints (75 µg) and D3 / K2 (100 µg), both at night: together they can pass the 80 µg BfR reference listed below, and the total our own rule holds it to is 360 µg a day. Across your plan, this is what the check watches.
OUR RULE: 200 MG A DAY
That formula carries 100 mg of coenzyme Q10 in the morning. With this one it would reach 300 mg, past the 200 mg daily total our own rule holds coenzyme Q10 to, so the two are checked together before they share a plan. That 200 mg is our rule, not an upper limit: the BfR reference our database applies is 100 mg a day, and this formula alone serves twice that.
UPPER LIMIT 5,000 MG
That BOOST formula carries 2,000 mg of EPA + DHA, also at night, which brings the two to 3,500 mg, under the 5,000 mg upper limit. EPA + DHA sits in six of our formulas, so it is your daily total that matters, not any one of them.
TALK TO A DOCTOR FIRST
Never with a vitamin K antagonist, such as warfarin, acenocoumarol or phenprocoumon: vitamin K2 works against the whole class, and coenzyme Q10 can reduce their effect too. Talk to a doctor first if you take any other anticoagulant, including a direct oral anticoagulant such as apixaban or dabigatran, an antiplatelet, blood pressure or diabetes medication, medicines that reduce fat absorption (orlistat, bile-acid sequestrants) or long courses of antibiotics; if you have a bleeding disorder or liver disease; if you are pregnant or breastfeeding; if you are under 18, as our file only supports coenzyme Q10 in under-18s under supervision; or if you are in cancer treatment. Stop it 1–2 weeks before planned surgery. It contains fish, its vitamin K2 is usually made from soy, and it is not suitable for vegans or vegetarians. Do not exceed the daily dose, do not use it in place of a varied and balanced diet, and keep it out of reach of young children. The app asks before it ever assigns this one.
WHERE THIS COMES FROM
Regulation (EU) 432/2012 on permitted health claims · EFSA Journal 2009;7(9):1228 on vitamin K · EFSA Journal 2010;8(10):1793 on coenzyme Q10 · Regulation (EU) 1169/2011 on nutrient reference values · EFSA Journal 2017 on the safety of hydroxytyrosol · upper intake references for EPA + DHA, coenzyme Q10 and vitamin K2. Every line on this page is tied to one of the 810 sources on file, and 443 of the 9,730 possible ingredient pairs in our library are documented so far.
WHERE IT COMES FROM
Six sources hold up this formula: the regulation that lets us make the claims, the EFSA opinions behind the vitamin K claim and against coenzyme Q10, the reference values for vitamin K, the safety opinion on the olive extract, and the upper references we measure the doses against.
Reviewed by VION nutrition team · last reviewed 16 September 2026
WHAT IS NOT PROVEN YET
This formula has not completed clinical validation. Its four ingredients rest on published work and, in two cases, on an authorised EU claim, but the combination itself has not been tested by us in a trial. When it is, the result goes on this page, whatever it says.
YOU DO NOT PICK YOUR FORMULAS
The questionnaire and your first weeks of data decide which six of the 29 end up in your device. This page exists so you can read what one of them is before that happens.
Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition. Nothing here replaces a healthcare professional.
Food supplement. Does not replace a varied diet or a healthy lifestyle. VION does not diagnose or treat any condition.
