COUNTED TOGETHER
Every other magnesium formula
Nine other VION formulas carry magnesium, from 100 to 200 mg, Sleep & circadian rhythm among them. Any one of them on the same day as this one would pass the 250 mg upper limit for supplemental magnesium, so the engine will not add it. The same count runs for vitamin D3 against its 100 µg limit.
SPLIT ACROSS WINDOWS
Iron
The iron formula is served in the morning, before food. This one keeps its 800 mg of calcium to the evening, so the two never meet in the same pour. That separation comes from our timing rules for each formula rather than from a documented pair in the interaction table, where calcium and iron are not yet listed. The reason is in the calcium file: in the same meal, calcium can cut the iron you absorb by around half.
TALK TO A DOCTOR FIRST
Not for everyone
Ruled out if you have high blood calcium, hyperparathyroidism or sarcoidosis; if you have advanced chronic kidney disease (stages 3–5) or active kidney stones, which block the calcium and vitamin D pairing and rule out the magnesium as well; or if you take a vitamin K antagonist such as warfarin or acenocoumarol, have an active clotting disorder (thrombophilia) or a mechanical heart valve. Magnesium is also contraindicated at high doses in myasthenia gravis. Ask a doctor first if you have lymphoma or a granulomatous disease such as tuberculosis, both of which our vitamin D file treats as relative contraindications because they can push blood calcium up; if you have a history of calcium oxalate kidney stones or a milder kidney problem, liver disease, a heart rhythm problem or high-grade heart block, or histamine intolerance; if you are being treated for cancer, since our sources ask for supervision on high-dose vitamin D and on magnesium alongside chemotherapy; if you are pregnant or breastfeeding; or if you have surgery planned, in which case the chondroitin is stopped two weeks before. The documented drug pairs come with an action, not just a warning: bisphosphonates, take the bisphosphonate fasting, wait at least 30 minutes, and keep the calcium and magnesium at least 2 hours away; levothyroxine, 4 hours apart; quinolone antibiotics, at least 2 hours before or 6 hours after the calcium, and 2 hours before or 4 to 6 hours after the magnesium; tetracyclines, at least 2 hours from both the calcium and the magnesium; digoxin, levels monitored, high-dose calcium avoided and low blood magnesium corrected before the drug is started; acid reducers (PPIs), blood magnesium monitored beyond three months of use, and the calcium served as citrate, which does not depend on stomach acid; apixaban, keep your vitamin K intake steady and ask cardiology before high doses. The pair table does not hold every drug our ingredient files list, so here is the rest of what they carry, with the rating each file gives it. Rated major: anticonvulsants such as phenytoin, phenobarbital or carbamazepine, and digoxin, both in our vitamin D file; thiazide diuretics, major in our vitamin D file and moderate in our calcium file; integrase inhibitors such as dolutegravir, 2 hours before or 6 hours after the calcium; cisplatin and muscle relaxants, both in our magnesium file. Rated moderate: systemic corticosteroids, in both the calcium and the vitamin D file; orlistat, in the vitamin D and the K2 file; statins, in the vitamin D file; bile acid sequestrants such as cholestyramine or colestipol, and long courses of antibiotics such as cephalosporins or ampicillin, both in the K2 file; lithium, in the calcium file; loop and potassium-sparing diuretics, aminoglycosides, amphotericin B and calcium-channel blockers, all in the magnesium file. None of them is in the pair table yet, so ask a doctor about any you take. Antiplatelet drugs carry the same label warning as the anticoagulants. Contains chicken protein, animal cartilage (bovine, porcine or marine) and soy-derived vitamin K2, as the MK-7 is usually fermented on soy: not for bird, egg, shellfish or soy allergies, and not vegan or vegetarian. Do not exceed the daily dose, keep out of reach of young children, and do not use it in place of a varied, balanced diet. The app asks before it ever assigns this one.
